Publications

Rizo JA, Spencer TE, Kelleher AM. Protocol for the establishment and characterization of an endometrial-derived epithelial organoid and stromal cell co-culture system. STAR Protoc. 2024 Feb 15;5(1):102894. doi: 10.1016/j.xpro.2024.102894. Epub ahead of print. PMID: 38363685

Spencer, T.E., Lowke, M.T., Davenport, K.M., Dhakal, P., and Kelleher, A.M. (2023). Single-cell insights into epithelial morphogenesis in the neonatal mouse uterus. Proceedings of the National Academy of Sciences 120, e2316410120.

Ahmad V, Yeddula SGR, Telugu B, Spencer TE, Kelleher AM. Development of Polarity-Reversed Endometrial Epithelial Organoids. Reproduction. 2024 Jan 1:REP-23-0478. doi: 10.1530/REP-23-0478. Epub ahead of print.

Rizo, J.A., Davenport, K.M., Winuthayanon, W., Spencer, T.E., and Kelleher, A.M. (2023). Estrogen receptor alpha regulates uterine epithelial lineage specification and homeostasis. Iscience 26.

Davenport, K.M., Ortega, M.S., Liu, H., O’Neil, E.V., Kelleher, A.M., Warren, W.C., and Spencer, T.E. (2023). Single-nuclei RNA sequencing (snRNA-seq) uncovers trophoblast cell types and lineages in the mature bovine placenta. Proceedings of the National Academy of Sciences 120, e2221526120.

Davenport, K.M., O’Neil, E.V., Ortega, M.S., Patterson, A., Kelleher, A.M., Warren, W.C., and Spencer, T.E. (2023). Single-cell insights into development of the bovine placenta. Biology of Reproduction, ioad123.Fitzgerald HC, Kelleher AM, Ranjit C, Schust DJ, Spencer TE. Basolateral secretions of human endometrial epithelial organoids impact stromal cell decidualization. Mol Hum Reprod. 2023 Feb 23:gaad007. doi: 10.1093/molehr/gaad007. Epub ahead of print. PMID: 36821428.

Kelleher AM, Allen CC, Davis DJ, Spencer TE. Prss29 Cre recombinase mice are useful to study adult uterine gland function. Genesis. 2022 Jul 22:e23493. doi: 10.1002/dvg.23493. PMID: 35866844.

Chi, R.A., Wang, T., Adams, N., Wu, S.P., Young, S.L., Spencer, T.E., and DeMayo, F. (2020). Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial Regulators. J Clin Endocrinol Metab 105. 10.1210/clinem/dgz117.

Dhakal, P., Kelleher, A.M., Behura, S.K., and Spencer, T.E. (2020). Sexually dimorphic effects of forkhead box a2 (FOXA2) and uterine glands on decidualization and fetoplacental development. Proc Natl Acad Sci U S A 117, 23952-23959. 10.1073/pnas.2014272117.

Fitzgerald, H.C., Dhakal, P., Behura, S.K., Schust, D.J., and Spencer, T.E. (2019). Self-renewing endometrial epithelial organoids of the human uterus. Proc Natl Acad Sci U S A 116, 23132-23142. 10.1073/pnas.1915389116.

Kelleher AM, Setlem R, Dantzer F, DeMayo FJ, Lydon JP, Kraus WL. Deficiency of PARP-1 and PARP-2 in the mouse uterus results in decidualization failure and pregnancy loss. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2109252118. doi: 10.1073/pnas.2109252118. PMID: 34580230; PMCID: PMC8501838.

Kelleher, A.M., Behura, S.K., Burns, G.W., Young, S.L., DeMayo, F.J., and Spencer, T.E. (2019). Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium. FASEB J 33, 8543-8554. 10.1096/fj.201900013R.

Kelleher, A.M., Milano-Foster, J., Behura, S.K., and Spencer, T.E. (2018). Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success. Nat Commun 9, 2435. 10.1038/s41467-018-04848-8.

Moraes, J.G.N., Behura, S.K., Geary, T.W., Hansen, P.J., Neibergs, H.L., and Spencer, T.E. (2018). Uterine influences on conceptus development in fertility-classified animals. Proc Natl Acad Sci U S A 115, E1749-E1758. 10.1073/pnas.1721191115.

Simintiras, C.A., Dhakal, P., Ranjit, C., Fitzgerald, H.C., Balboula, A.Z., and Spencer, T.E. (2021). Capture and metabolomic analysis of the human endometrial epithelial organoid secretome. Proc Natl Acad Sci U S A 118. 10.1073/pnas.2026804118.